Doctors say therapy that genetically modifies person’s T-cells could offer cure for chronic autoimmune disease

Five lupus patients in England are in remission after being treated with a revolutionary therapy that genetically modifies their own cells, in a medical breakthrough that could offer people a cure, doctors have said.

CAR (chimeric antigen receptor) T-cell therapy involves removing a type of white blood cell also called T lymphocytes, which are crucial for hunting out infected or damaged cells, and engineering them to spot and destroy disease. The T-cells are then fed back into the patient via an infusion to reset their immune system.

London, the east of England and the West Midlands have highest number of cases, as UKHSA urges families to get children vaccinated

Two children in England have died from measles, health officials say, as data shows more than 100 new reported cases in the last fortnight.

The UK Health Security Agency (UKHSA) said on Thursday that two children had died this year, one from “acute measles” and the other from the “late effects of measles”.

Senior medical staff call for solutions to tackle root causes of excess deaths amid tenfold increase in a decade

More than 1,300 patients a month in England are dying needlessly due to long A&E waits, a tenfold rise in a decade, figures suggest.

There were more than 300 deaths linked to long waits every week in 2025, up from 30 a week in 2015, according to analysis by the Royal College of Emergency Medicine.